OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers (OPEN-IT)
Marginal Ulcer
About this trial
This is an interventional treatment trial for Marginal Ulcer focused on measuring marginal ulcer, bariatric surgery, gastric bypass, open capsule
Eligibility Criteria
Inclusion Criteria: Subjects diagnosed with marginal ulceration post-gastric bypass on upper endoscopy Exclusion Criteria: Refusal to start PPI medication OR current open-capsule PPI use at the time of diagnosis of the marginal ulcer
Sites / Locations
- Cleveland Clinic FoundationRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Open-capsule
Intact-capsule
Subjects in this arm will be treated with omeprazole 40 milligrams twice daily (or alternative medication if not covered by the subject's insurance) taken as an open-capsule until confirmed ulcer healing.
Subjects in this arm will be treated with omeprazole 40 milligrams twice daily (or alternative medication if not covered by the subject's insurance) taken as an intact-capsule until confirmed ulcer healing or potential cross-over.