Effect of Acupuncture and Low Caloric Diet on Primary Hypothyroidism and Irregular Menstruation in Infertile Women
Primary Hypothyroidism, Acupuncture, Irregular Menstruation
About this trial
This is an interventional supportive care trial for Primary Hypothyroidism focused on measuring primary hypothyroidism, acupuncture, low caloric diet, infertile women
Eligibility Criteria
Inclusion Criteria: Sixty PCOS women will be evaluated for presence of hirsutism, acne, irregular menses. They will be diagnosed for presence of cysts by Ultrasonography apparatus. They will complain from primary hypothyroidism. Their thyroid-stimulating hormone (TSH) will be >4.0mu/l and free tetraiodothyronine (FT4) will be <0.8ng/dl. Their luteinizing hormone / follicle-stimulating hormone (LH/FSH) ratio will be <1. Their age will range from 20-35 years old. Their body mass index (BMI) will be > 25 kg/m2 and < 39.9 kg/m2. Exclusion Criteria: History of previous neurological disorders, previous thyroidectomy, and surgical removal of uterus. Presence of hemorrhage, carcinoma, metal implants and using of immune suppressant drugs. Presence of endometriosis, uterine fibroids, primary ovary insufficiency, fallopian tube damage or blockage, pelvic adhesion, autoimmune disorders, implantation failure, and infections.
Sites / Locations
- Eman Sedky
Arms of the Study
Arm 1
Arm 2
Experimental
Other
study group
control group
Each patient in the study group will be instructed about the beneficial effect of the acupuncture. Each woman in the study group will assume side lying position with uncovered treatment area, thyroxine tablets (levothyroxine) (1tablet per day) describe by the physician. Levothyroxine is usually taken 30-60 minutes before breakfast, or four hours after food, as certain substance such as food and calcium can inhabit the absorption of levothyroxine. low caloric diet regime consisting of 1200 to 800Kcal/ day for 4 months. Fine sterile needles will be used with a size 0.25x25mm. They will be inserted to various depths (2-5 cm) at acupoints points on the body according to site and fat deposition. 16 needles will be used in the treatment
Each woman in both groups (control and study) will receive thyroxine tablets (levothyroxine) (1tablet per day) describe by the physician. Levothyroxine is usually taken 30-60 minutes before breakfast, or four hours after food, as certain substance such as food and calcium can inhabit the absorption of levothyroxine Each woman in both groups will follow a low caloric diet regime consisting of 1200 to 800Kcal/ day for 4 months. The regime will start with 1200 Kcal for the first month and 1100 for the second month then 900 Kcal for the third month until reach 800 Kcal in fourth month.