Alpha-Lipoic Acid in Patients With Sepsis
Sepsis
About this trial
This is an interventional treatment trial for Sepsis focused on measuring Alpha Lipoic Acid, MCP-1, Mortality, Vasopressors, Efficacy, Safety
Eligibility Criteria
Inclusion Criteria: Patients 18 years or older Patients able to receive oral or enteral medication Patients with confirmed diagnosis of sepsis according to Sepsis-3 definition; documented or suspected infection associated with organ dysfunction identified by acute change in total SOFA score of 2 points or more. Exclusion Criteria: Patients with septic shock defined as patients with sepsis who has persistent hypotension that necessitates the use of vasopressors to maintain MAP greater than or equal to 65mmHg and a blood lactate level greater than 2 mmol/L (18 mg/dL) despite absence of hypovolemia. Patients on mechanical ventilation at baseline. Pregnant women Patients already receiving ALA supplementation before ICU admission
Sites / Locations
- Ain Shams University Specialized HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Alpha-Lipoic Acid Group
Control Group