Artificial Intelligence to Predict Surgical Outcomes and Assess Pain Neuromodulation in Trigeminal Neuralgia Subjects
Trigeminal Neuralgia, Trigeminal Nerve Diseases, Virtual Reality
About this trial
This is an interventional treatment trial for Trigeminal Neuralgia
Eligibility Criteria
Inclusion Criteria: diagnosis of TN according to the International Classification of Headache Disorders, third edition (ICHD-3) criteria; age >18 years; indication to undergo radiosurgical treatment; willingness and ability to comply with scheduled visits and other trial procedures. Exclusion Criteria: Any person unable to lie still within the environment of the MRI scanner for the required period to perform the study and those where MRI scanning is contraindicated; metal implants, pacemaker, etc.; Pregnancy or breastfeeding; Any significant psychiatric disease; Use of illicit drugs; Brain pathology shown by brain MRI and/or neurophysiological examination; Any person unable to understand and follow the instructions of the investigators; Any other condition according to the Investigator would make the subject unsuitable for the study.
Sites / Locations
- IRCCS San RaffaeleRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
No Intervention
GKRS-VR training
Control Group
Healthy subjects
GKRS-VR group will undergo GKRS and neuromodulation based on Virtual Reality sensorimotor rehabilitation using an immersive system
Control group (CT) will undergo only GKRS
Age- and sex-matched healthy subjects recruited to compare neuropsychological,clinical and structural/functional magnetic resonance imaging characteristics at baseline.