Temporomandibular Joint Arthrocentesis With Infiltration of PRP + Ropivacaine Versus PRP

Inclusion Criteria: Male and female subjects between the ages of 18-99 years; For women of reproductive potential: use of highly effective contraception for at least 1 month prior to the first visit and agreement to use such a method during participation in the study; In the opinion of the investigator, the subject is capable of understanding and comprehending the study in question; The subject signs the written informed consent form and provides the necessary privacy clearance prior to the start of any study procedures; Patients with TMD with an indication for TMJ arthrocentesis: clinical and imaging diagnosis of unilateral or bilateral intra-articular disorder; Magnetic resonance imaging (MRI) assessing the intra-articular derangement; Radiological findings that most components of the joint were salvageable; Dimitroulis classification between 2 and 3. Exclusion Criteria: Subject has had other previous minimally invasive or invasive treatment for TMD; Subject has any contraindication to the use of ropivacaine according to the Ropivacaine (Fresenius Kabi) bulletin; Subject has a history of allergy to any drug in the study; Subject taking analgesic medication prior to treatment for other conditions; The subject has an inability to interpret pain scales or to read and interpret the study's target questionnaire; Women who are pregnant or breastfeeding. For women of reproductive potential, use of highly effective contraception for at least 1 month prior to the first visit is required (Combined oral contraceptive pill, vaginal ring, male and female condom, intrauterine device, diaphragm, injectable hormonal contraceptive) and agreement to use such a method during study participation. Subjects under 18 and over 99 years old; Subjects diagnosed with the following conditions cannot participate in the study: cardiovascular disorders, peripheral vascular disease, arrhythmias, auriculoventricular conduction disorders, heart failure; hypotension, epileptic patients, patients with liver and kidney disease, patients with porphyria, patients with acidosis. Subjects with severe medical problems and mental illness.