Astringency and Oral Health
Saliva Altered, Taste, Altered
About this trial
This is an interventional basic science trial for Saliva Altered
Eligibility Criteria
Inclusion Criteria: PROP insensitive individuals (PROP non-tasters; homozygous recessive for TAS2R38 gene) PROP high-sensitive individuals (PROP super-tasters; homozygous dominant for TAS2R38 gene) Overall healthy; good oral health and hygiene routine Current on a routine checkup by a oral/dental health professional Recently underwent dental/cleaning by a oral/dental health professional No ongoing oral health problems Agree to use intervention material as prescribed Agree to refrain from using any other oral rinse material during the term of the study Exclusion Criteria: PROP medium-taster individuals (heterozygous for TAS2R38 gene) Taste or smell dysfunction Pregnant or nursing Oral piercings Smoking Use of medications other than birth control
Sites / Locations
- Rutgers University, Department of Food ScienceRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
PROP non-taster subjects
PROP super-taster subjects
This arm will comprise of PROP non-taster subjects. Subjects will use a cranberry-derived oral rinse twice a day for 11 days following a 3-day plain water-rinse period.
This arm will comprise of PROP super-taster subjects. Subjects will use a cranberry-derived oral rinse twice a day for 11 days following a 3-day plain water-rinse period.