A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems
Plaque, Gum Disease
About this trial
This is an interventional prevention trial for Plaque
Eligibility Criteria
Inclusion Criteria: Subjects, ages 18-70, inclusive. Availability for the six-month duration of the clinical research study. Good general health. Initial gingivitis index of at least 1.0 as determined by the use of the Loe-Silness Gingival Index. Initial plaque index of at least 1.5 as determined by the use of the Quigley-Hein Plaque Index. Signed Informed Consent Form Exclusion Criteria: Presence of orthodontic bands. Tumor(s) of the soft or hard tissues of the oral cavity. Advanced periodontal disease (purulent exudate, tooth mobility, and/or extensive loss of periodontal attachment or alveolar bone). Five or more carious lesions requiring immediate restorative treatment. Antibiotic use any time during the one-month period prior to entry into the study. Participation in any other clinical study or test panel within the one month prior to entry into the study. Dental prophylaxis during the past two weeks prior to baseline examinations. History of allergies to oral care/personal care consumer products or their ingredients. On any prescription medicines that might interfere with the study outcome. An existing medical condition that prohibits eating or drinking for periods up to 4 hours. History of alcohol or drug abuse. Self-reported pregnant or lactating subjects
Sites / Locations
- Clinica Odontoiatrica Montesani
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride Mouthwash
0.057% sodium fluoride Mouthwash
mouthwash
mouthwash