Effects of Topical Hyaluronic Acid Gel on Postoperative Pain and Wound Healing

Inclusion Criteria: Males and females, between 18-70 years of age Informed Consent Form signed and availability for the duration of the study Good general health (absence of any condition that, in the opinion of the Principal Investigator, might constitute a risk to the subject while participating in the study Clinical indication for mucogingival surgery that requires a de-epithelialized gingival graft (DGG) from the palate Willingness to provide information related to their medical history Minimum of 10 uncrowned permanent natural teeth (excluding third molars) Normal salivary flow Exclusion Criteria: Oral pathology, chronic disease, or a history of allergy to testing products Subject using anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory medication or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study Subject participating in any other clinical study Subject pregnant or breastfeeding Subject allergic to oral care products, personal care consumer products, or their ingredients Extended use of antibiotics or therapeutic mouthwash any time during the three months prior to entry into the study A medical history reporting that the subject has a current systemic or autoimmune disease, such as diabetes, lupus, etc Ongoing use of medications known to affect the gingival tissues (i.e. calcium channel blockers, phenytoin, cyclosporine)