Underwater Versus Conventional Endoscopic Mucosal Resection in the Treatment of Non-pedunculated Colorectal Polyps
Colorectal Polyp, Colorectal Neoplasms
About this trial
This is an interventional treatment trial for Colorectal Polyp focused on measuring colorectal polyp, underwater endoscopic mucosal resection, conventional endoscopic mucosal resection
Eligibility Criteria
Inclusion Criteria: Age > 18 years Non-pedunculated polyps of 10 mm or more in size Type 1 or 2 according to NBI International Colorectal Endoscopy (NICE) classification Patients must sign an informed consent form prior to registration in study Exclusion Criteria: Lesions with signs of deep invasion (hard, friable tissue, poor mobility, positive "non-lifting" sign) Type 3 according to NICE classification Colorectal cancer Patients with unstable chronic disease (melitus diabetes, hypertension, heart failure, kidney failure, liver failure, chronic obstructive pulmonary disease) Hemostasis disorder (INR > 1.5; platelets < 100000/mm3)
Sites / Locations
- University of Medicine and Pharmacy at Ho Chi Minh cityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Underwater endoscopic mucosal resection
Conventional endoscopic mucosal resection
Intervention: Non-pedunculated polyps will be removed by underwater endoscopic mucosal resection. The UEMR procedure included the following: (1) complete deflation of the colorectal lumen; (2) total immersion of the lesion in normal saline using a mechanical water pump; (3) snaring the lesion and the surrounding mucosa; and (4) resection using electrocautery.
Intervention: Non-pedunculated polyps will be removed by conventional endoscopic mucosal resection. The CEMR procedure included the following: (1) needle injection of normal saline into the submucosa; (2) entrapment of the mucosal protrusion with a snare; and (3) resection applying the same electrocautery setting as was used for UEMR.