Evaluating the Safety and Efficacy of Autologous Adipose Tissue-derived Mesenchymal Stem Cell Transplantation on Proinflammatory Cytokines and Anti-inflammatory Cytokines on Ageing-related Low-grade Inflammation Patients.

Inclusion Criteria: Male or female patient, age 40 to 64 years. The inflammatory aging patient as defined in the protocol as TNF alpha or IL6 at the time of screening was higher than the 95% healthy percentile value declared by the test system manufacturer. Have at least 2 of the 3 following diseases: Diabetes type II Dyslipidemia Obesity [The diagnosis and determination of accompanying diseases (Diabetes, Dyslipidemia, Obesity) will be carried out according to the general guidance of the MOH Vietnam]. Patients are using stable drugs for co-infection (diabetes mellitus, dyslipidemia, obesity) stably in the past 3 months. Agree to participate in research and agree to comply with the research examination and evaluation process. Exclusion Criteria: Patients with a blood-clotting disorder or hemophilia Patients with severe heart failure Acute respiratory pathology at the time of screening Patients with cancer or other acute illness need treatment. Patients with a history of allergy to anesthetics, anesthesia, and antibiotics Patients are planning to participate in another clinical trial while participating in the study There are other conditions or circumstances in which it is difficult for researchers to ensure adherence to treatment in the judgment of researchers.