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A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

Primary Purpose

SARS-CoV-2, Influenza

Status
Active
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
Fluarix
mRNA-1083.1
mRNA-1083.2
mRNA-1083.3
mRNA-1010.4
mRNA-1283.222
mRNA-1273.222
mRNA-1010
Fluzone HD
Sponsored by
ModernaTX, Inc.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for SARS-CoV-2 focused on measuring mRNA-1083, mRNA-1083 Vaccine, SARS-CoV-2, SARS-CoV-2 Vaccine, Coronavirus, Virus Diseases, Messenger RNA, Influenza Vaccine, Moderna

Eligibility Criteria

18 Years - 79 Years (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Key Inclusion Criteria: Body mass index (BMI) of 18 kilograms (kg)/m2 to 35 kg/square meter (m^2) (inclusive) at the Screening Visit. Healthy as determined by medical evaluation, including medical history, physical examination, and laboratory tests. For female participants of childbearing potential: negative pregnancy test, adequate contraception or has abstained from all activities that could result in pregnancy for at least 28 days prior to Day 1, agreement to continue adequate contraception through 90 days following vaccine administration, and not currently breastfeeding. Fully vaccinated for COVID-19 primary series according to the locally authorized or approved regimen, and their last COVID-19 vaccine (primary series or booster) was ≥120 days prior to Day 1. Key Exclusion Criteria: Participant is acutely ill or febrile (temperature ≥38.0 degrees Celsius [°C]/100.4 degrees Fahrenheit [°F]) 72 hours prior to or at the Screening Visit or Day 1. Any medical, psychiatric, or occupational condition, including reported history of drug or alcohol abuse, that, in the opinion of the Investigator, might pose additional risk due to participation in the clinical trial or could interfere with the interpretation of study results. Participant has received systemic immunosuppressants for >14 days in total within 180 days prior to Screening Visit (for glucocorticoids ≥10 milligrams [mg]/day of prednisone or equivalent) or is anticipating the need for systemic immunosuppressive treatment at any time during participation in the clinical trial (including intra-articular steroid injections). Inhaled, nasal, and topical steroids are allowed. Participant has received or plans to receive any vaccine authorized or approved by a local health agency ≤28 days prior to study intervention administration or plans to receive a vaccine authorized or approved by a local health agency within 28 days after study intervention administration. Participant has received a seasonal influenza vaccine or any other investigational influenza vaccine within 150 days prior to Day 1. Participant tested positive for influenza by local health authority-approved testing methods ≤150 days prior to Day 1. Participant has had close contact to someone with COVID-19 as defined by the Centers for Disease Control and Prevention (CDC) in the past 10 days prior to Day 1. Participant has donated ≥450 milliliters (mL) of blood products within 28 days prior to the Screening Visit or plans to donate blood products during the clinical trial. Note: Other inclusion/exclusion criteria may apply.

Sites / Locations

  • Chandler Clinical Trials
  • Benchmark Research
  • Marvel Clinical Research
  • Central Valley Research
  • Benchmark Research
  • Tekton Research
  • Accel Research Sites
  • CenExel
  • Nature Coast Clinical Research
  • Jacksonville Center For Clinical Research
  • Accel Research Sites
  • Suncoast Research Group
  • Centricity Research
  • Accel Research Site
  • CenExel iResearch
  • Lifeline Primary Care
  • Koch Family Medicine
  • Optimal Research
  • DM Clinical Research
  • Johnson County Clin-Trials
  • Tekton Research
  • Versailles Family Medicine
  • Velocity Clinical research
  • Benchmark Research
  • DelRicht Research
  • DelRicht Research
  • Annapolis Internal Medicine
  • Velocity Clinical Research
  • DM Clinical Research
  • Vida Clinical Studies
  • DelRicht Research
  • Clay Platte Family Medicine
  • Velocity Clinical Research
  • Velocity Clinical Research
  • Excel Clinical Research
  • CCT Research
  • Las Vegas Clinical Trials
  • Rochester Clinical Research
  • Tryon Medical Partners
  • Trial Management Associates
  • CTI Clinical Research Center
  • Velocity Clinical Research
  • Velocity Clinical Research
  • Centricity Research
  • WellNow Urgent Care & Research
  • Lynn Institute of East Oklahoma
  • DelRicht Research
  • Tekton Research Inc
  • DM Clinical Research
  • Mercado Medical Practice
  • DelRicht Research
  • Trial Management Associates
  • Medical Care
  • DelRicht Research
  • Benchmark Research
  • Tekton Research
  • Tekton Research
  • Benchmark Research
  • Cyfair Clinical Research
  • Texas Center for Drug Development
  • DelRicht Research
  • Benchmark Research
  • Tekton Research
  • CCT Research
  • Ogden Clinic
  • JBR Clinical Research
  • Meridian Clinical Research
  • Velocity Clinical Research
  • Wenatchee Valley Hospital & Clinics Campus

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm 5

Arm 6

Arm 7

Arm 8

Arm 9

Arm 10

Arm 11

Arm 12

Arm 13

Arm 14

Arm 15

Arm 16

Arm 17

Arm 18

Arm 19

Arm 20

Arm 21

Arm 22

Arm 23

Arm 24

Arm Type

Experimental

Experimental

Experimental

Experimental

Experimental

Experimental

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Experimental

Experimental

Experimental

Experimental

Experimental

Experimental

Experimental

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Active Comparator

Arm Label

Cohort A2: mRNA-1083.1 Dose B

Cohort A3: mRNA-1083.1 Dose C

Cohort A4: mRNA-1083.2 Dose A

Cohort A5: mRNA-1083.2 Dose B

Cohort A6: mRNA-1083.2 Dose C

Cohort A7: mRNA-1083.3

Cohort A8: mRNA-1010.4

Cohort A9: mRNA-1283.222

Cohort A10: mRNA-1273.222

Cohort A11: mRNA-1010

Cohort A12: Fluarix

Cohort A13: Fluzone HD

Cohort B1: mRNA-1083.1 Dose A

Cohort B2: mRNA-1083.1 Dose B

Cohort B3: mRNA-1083.1 Dose C

Cohort B4: mRNA-1083.2 Dose A

Cohort B5: mRNA-1083.2 Dose B

Cohort B6: mRNA-1083.2 Dose C

Cohort B7: mRNA-1083.3

Cohort B8: mRNA-1010.4

Cohort B9: mRNA-1283.222

Cohort B10: mRNA-1273.222

Cohort B11: mRNA-1010

Cohort B12: Fluarix

Arm Description

Participants will receive single intramuscular (IM) injection of mRNA-1083.1 at Dose Level B on Day 1.

Participants will receive single IM injection of mRNA-1083.1 at Dose Level C on Day 1.

Participants will receive single IM injection of mRNA-1083.2 at Dose Level A on Day 1.

Participants will receive single IM injection of mRNA-1083.2 at Dose Level B on Day 1.

Participants will receive single IM injection of mRNA-1083.2 at Dose Level C on Day 1.

Participants will receive single IM injection of mRNA-1083.3 on Day 1.

Participants will receive single IM injection of mRNA-1010.4 on Day 1.

Participants will receive single IM injection of mRNA-1283.222 on Day 1.

Participants will receive single IM injection of mRNA-1273.222 on Day 1.

Participants will receive single IM injection of mRNA-1010 on Day 1.

Participants will receive single IM injection of Fluarix on Day 1.

Participants will receive single IM injection of Fluzone HD on Day 1.

Participants will receive single IM injection of mRNA-1083.1 at Dose Level A on Day 1.

Participants will receive single IM injection of mRNA-1083.1 at Dose Level B on Day 1.

Participants will receive single IM injection of mRNA-1083.1 at Dose Level C on Day 1.

Participants will receive single IM injection of mRNA-1083.2 at Dose Level A on Day 1.

Participants will receive single IM injection of mRNA-1083.2 at Dose Level B on Day 1.

Participants will receive single IM injection of mRNA-1083.2 at Dose Level C on Day 1.

Participants will receive single IM injection of mRNA-1083.3 on Day 1.

Participants will receive single IM injection of mRNA-1010.4 on Day 1.

Participants will receive single IM injection of mRNA-1283.222 on Day 1.

Participants will receive single IM injection of mRNA-1273.222 on Day 1.

Participants will receive single IM injection of mRNA-1010 on Day 1.

Participants will receive single IM injection of Fluarix on Day 1.

Outcomes

Primary Outcome Measures

Number of Participants With Solicited Local and Systemic Adverse Reactions (ARs)
Number of Participants With Unsolicited Adverse Events (AEs) and Severe AEs
Number of Participants With Unsocilited Medically Attended Adverse Events (MAAEs), Adverse Events of Special Interest (AESIs), Serious Adverse Events (SAEs), and AEs Leading to Discontinuation of Study

Secondary Outcome Measures

Change From Baseline in Geometric Mean Titer (GMT) of Antibodies for Influenza, as Measured by Hemagglutination Inhibition (HAI) Assay
Change From Baseline in GMT of Antibodies for SARS-CoV-2, as Measured by Pseudovirus Neutralization Assay (PsVNA)
Change From Baseline in Geometric Mean Fold-Rise (GMFR) of Antibodies for Influenza, as Measured by HAI Assay
Change From Baseline in GMFR of Antibodies for SARS-CoV-2, as Measured by PsVNA
Influenza: Percentage of Participants with Seroconversion, as Measured by HAI Assay
Seroconversion is defined as a Day 29 and Day 181 titer ≥1:40 if baseline is <1:10 or a 4-fold or greater rise if baseline is ≥1:10 in anti-HA antibodies measured by HAI assay.
SARS-CoV-2: Percentage of Participants with Seroresponse, as Measured by PsVNA
Seroresponse is defined as a Day 29 and Day 181 titer ≥4-fold if baseline is ≥lower limit of quantification (LLOQ) or ≥4*LLOQ if baseline titer is <LLOQ in neutralizing antibody (nAb) titers measured by PsVNA.

Full Information

First Posted
April 24, 2023
Last Updated
September 8, 2023
Sponsor
ModernaTX, Inc.
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1. Study Identification

Unique Protocol Identification Number
NCT05827926
Brief Title
A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults
Official Title
A Phase 1/2, Randomized, Observer-blind, Active-Control Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-based Influenza and SARS-CoV-2 Multi-component Vaccines in Healthy Adults
Study Type
Interventional

2. Study Status

Record Verification Date
September 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
April 14, 2023 (Actual)
Primary Completion Date
December 20, 2023 (Anticipated)
Study Completion Date
December 20, 2023 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
ModernaTX, Inc.

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No

5. Study Description

Brief Summary
The purpose of this study is to generate sufficient safety, reactogenicity, and immunogenicity data to enable selection of an mRNA-1083 vaccine composition and dose level to evaluate in a subsequent Phase 3 clinical trial in adults.
Detailed Description
Participants will be enrolled into 1 of 2 age cohorts: Cohort A for adults ≥65 to <80 years of age or Cohort B for adults ≥18 to <65 year of age. In Cohort A, approximately 600 participants will be randomized (in equal allocation ratio) into the investigational treatment arms, stratified by influenza vaccine status in the most recent influenza season (received or not received since September 2022). In Cohort B, approximately 624 participants will be randomized (in equal allocation ratio) into the investigational treatment arms, stratified by 2 age groups: ≥18 to <50 years and ≥50 to <65 years of age and by influenza vaccine status in the most recent influenza season (received or not received since September 2022).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
SARS-CoV-2, Influenza
Keywords
mRNA-1083, mRNA-1083 Vaccine, SARS-CoV-2, SARS-CoV-2 Vaccine, Coronavirus, Virus Diseases, Messenger RNA, Influenza Vaccine, Moderna

7. Study Design

Primary Purpose
Prevention
Study Phase
Phase 1, Phase 2
Interventional Study Model
Parallel Assignment
Masking
Outcomes Assessor
Allocation
Randomized
Enrollment
1231 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Cohort A2: mRNA-1083.1 Dose B
Arm Type
Experimental
Arm Description
Participants will receive single intramuscular (IM) injection of mRNA-1083.1 at Dose Level B on Day 1.
Arm Title
Cohort A3: mRNA-1083.1 Dose C
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.1 at Dose Level C on Day 1.
Arm Title
Cohort A4: mRNA-1083.2 Dose A
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.2 at Dose Level A on Day 1.
Arm Title
Cohort A5: mRNA-1083.2 Dose B
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.2 at Dose Level B on Day 1.
Arm Title
Cohort A6: mRNA-1083.2 Dose C
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.2 at Dose Level C on Day 1.
Arm Title
Cohort A7: mRNA-1083.3
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.3 on Day 1.
Arm Title
Cohort A8: mRNA-1010.4
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1010.4 on Day 1.
Arm Title
Cohort A9: mRNA-1283.222
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1283.222 on Day 1.
Arm Title
Cohort A10: mRNA-1273.222
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1273.222 on Day 1.
Arm Title
Cohort A11: mRNA-1010
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1010 on Day 1.
Arm Title
Cohort A12: Fluarix
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of Fluarix on Day 1.
Arm Title
Cohort A13: Fluzone HD
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of Fluzone HD on Day 1.
Arm Title
Cohort B1: mRNA-1083.1 Dose A
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.1 at Dose Level A on Day 1.
Arm Title
Cohort B2: mRNA-1083.1 Dose B
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.1 at Dose Level B on Day 1.
Arm Title
Cohort B3: mRNA-1083.1 Dose C
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.1 at Dose Level C on Day 1.
Arm Title
Cohort B4: mRNA-1083.2 Dose A
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.2 at Dose Level A on Day 1.
Arm Title
Cohort B5: mRNA-1083.2 Dose B
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.2 at Dose Level B on Day 1.
Arm Title
Cohort B6: mRNA-1083.2 Dose C
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.2 at Dose Level C on Day 1.
Arm Title
Cohort B7: mRNA-1083.3
Arm Type
Experimental
Arm Description
Participants will receive single IM injection of mRNA-1083.3 on Day 1.
Arm Title
Cohort B8: mRNA-1010.4
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1010.4 on Day 1.
Arm Title
Cohort B9: mRNA-1283.222
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1283.222 on Day 1.
Arm Title
Cohort B10: mRNA-1273.222
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1273.222 on Day 1.
Arm Title
Cohort B11: mRNA-1010
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of mRNA-1010 on Day 1.
Arm Title
Cohort B12: Fluarix
Arm Type
Active Comparator
Arm Description
Participants will receive single IM injection of Fluarix on Day 1.
Intervention Type
Biological
Intervention Name(s)
Fluarix
Intervention Description
quadrivalent seasonal influenza vaccine
Intervention Type
Biological
Intervention Name(s)
mRNA-1083.1
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
mRNA-1083.2
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
mRNA-1083.3
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
mRNA-1010.4
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
mRNA-1283.222
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
mRNA-1273.222
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
mRNA-1010
Intervention Description
Sterile liquid for injection
Intervention Type
Biological
Intervention Name(s)
Fluzone HD
Intervention Description
quadrivalent seasonal influenza vaccine
Primary Outcome Measure Information:
Title
Number of Participants With Solicited Local and Systemic Adverse Reactions (ARs)
Time Frame
Up to Day 7 (7 days after vaccination)
Title
Number of Participants With Unsolicited Adverse Events (AEs) and Severe AEs
Time Frame
Up to Day 28 (28 days after vaccination)
Title
Number of Participants With Unsocilited Medically Attended Adverse Events (MAAEs), Adverse Events of Special Interest (AESIs), Serious Adverse Events (SAEs), and AEs Leading to Discontinuation of Study
Time Frame
Day 1 through Day 181
Secondary Outcome Measure Information:
Title
Change From Baseline in Geometric Mean Titer (GMT) of Antibodies for Influenza, as Measured by Hemagglutination Inhibition (HAI) Assay
Time Frame
Baseline (Day 1), Day 29, and Day 181
Title
Change From Baseline in GMT of Antibodies for SARS-CoV-2, as Measured by Pseudovirus Neutralization Assay (PsVNA)
Time Frame
Baseline (Day 1), Day 29, and Day 181
Title
Change From Baseline in Geometric Mean Fold-Rise (GMFR) of Antibodies for Influenza, as Measured by HAI Assay
Time Frame
Baseline (Day 1), Day 29, and Day 181
Title
Change From Baseline in GMFR of Antibodies for SARS-CoV-2, as Measured by PsVNA
Time Frame
Baseline (Day 1), Day 29, and Day 181
Title
Influenza: Percentage of Participants with Seroconversion, as Measured by HAI Assay
Description
Seroconversion is defined as a Day 29 and Day 181 titer ≥1:40 if baseline is <1:10 or a 4-fold or greater rise if baseline is ≥1:10 in anti-HA antibodies measured by HAI assay.
Time Frame
Baseline (Day 1) to Day 29, and Day 181
Title
SARS-CoV-2: Percentage of Participants with Seroresponse, as Measured by PsVNA
Description
Seroresponse is defined as a Day 29 and Day 181 titer ≥4-fold if baseline is ≥lower limit of quantification (LLOQ) or ≥4*LLOQ if baseline titer is <LLOQ in neutralizing antibody (nAb) titers measured by PsVNA.
Time Frame
Baseline (Day 1) to Day 29, and Day 181

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
79 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Key Inclusion Criteria: Body mass index (BMI) of 18 kilograms (kg)/m2 to 35 kg/square meter (m^2) (inclusive) at the Screening Visit. Healthy as determined by medical evaluation, including medical history, physical examination, and laboratory tests. For female participants of childbearing potential: negative pregnancy test, adequate contraception or has abstained from all activities that could result in pregnancy for at least 28 days prior to Day 1, agreement to continue adequate contraception through 90 days following vaccine administration, and not currently breastfeeding. Fully vaccinated for COVID-19 primary series according to the locally authorized or approved regimen, and their last COVID-19 vaccine (primary series or booster) was ≥120 days prior to Day 1. Key Exclusion Criteria: Participant is acutely ill or febrile (temperature ≥38.0 degrees Celsius [°C]/100.4 degrees Fahrenheit [°F]) 72 hours prior to or at the Screening Visit or Day 1. Any medical, psychiatric, or occupational condition, including reported history of drug or alcohol abuse, that, in the opinion of the Investigator, might pose additional risk due to participation in the clinical trial or could interfere with the interpretation of study results. Participant has received systemic immunosuppressants for >14 days in total within 180 days prior to Screening Visit (for glucocorticoids ≥10 milligrams [mg]/day of prednisone or equivalent) or is anticipating the need for systemic immunosuppressive treatment at any time during participation in the clinical trial (including intra-articular steroid injections). Inhaled, nasal, and topical steroids are allowed. Participant has received or plans to receive any vaccine authorized or approved by a local health agency ≤28 days prior to study intervention administration or plans to receive a vaccine authorized or approved by a local health agency within 28 days after study intervention administration. Participant has received a seasonal influenza vaccine or any other investigational influenza vaccine within 150 days prior to Day 1. Participant tested positive for influenza by local health authority-approved testing methods ≤150 days prior to Day 1. Participant has had close contact to someone with COVID-19 as defined by the Centers for Disease Control and Prevention (CDC) in the past 10 days prior to Day 1. Participant has donated ≥450 milliliters (mL) of blood products within 28 days prior to the Screening Visit or plans to donate blood products during the clinical trial. Note: Other inclusion/exclusion criteria may apply.
Facility Information:
Facility Name
Chandler Clinical Trials
City
Chandler
State/Province
Arizona
ZIP/Postal Code
85224-6231
Country
United States
Facility Name
Benchmark Research
City
Colton
State/Province
California
ZIP/Postal Code
92324
Country
United States
Facility Name
Marvel Clinical Research
City
Huntington Beach
State/Province
California
ZIP/Postal Code
92647-6835
Country
United States
Facility Name
Central Valley Research
City
Modesto
State/Province
California
ZIP/Postal Code
95350-5365
Country
United States
Facility Name
Benchmark Research
City
Sacramento
State/Province
California
ZIP/Postal Code
95864-3102
Country
United States
Facility Name
Tekton Research
City
Longmont
State/Province
Colorado
ZIP/Postal Code
80501-6461
Country
United States
Facility Name
Accel Research Sites
City
DeLand
State/Province
Florida
ZIP/Postal Code
32720-0834
Country
United States
Facility Name
CenExel
City
Hollywood
State/Province
Florida
ZIP/Postal Code
33024
Country
United States
Facility Name
Nature Coast Clinical Research
City
Inverness
State/Province
Florida
ZIP/Postal Code
34452
Country
United States
Facility Name
Jacksonville Center For Clinical Research
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32216
Country
United States
Facility Name
Accel Research Sites
City
Maitland
State/Province
Florida
ZIP/Postal Code
32751
Country
United States
Facility Name
Suncoast Research Group
City
Miami
State/Province
Florida
ZIP/Postal Code
33135-1687
Country
United States
Facility Name
Centricity Research
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31904
Country
United States
Facility Name
Accel Research Site
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30030-2615
Country
United States
Facility Name
CenExel iResearch
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30030
Country
United States
Facility Name
Lifeline Primary Care
City
Lilburn
State/Province
Georgia
ZIP/Postal Code
30047-2832
Country
United States
Facility Name
Koch Family Medicine
City
Morton
State/Province
Illinois
ZIP/Postal Code
61550
Country
United States
Facility Name
Optimal Research
City
Peoria
State/Province
Illinois
ZIP/Postal Code
61614-4885
Country
United States
Facility Name
DM Clinical Research
City
River Forest
State/Province
Illinois
ZIP/Postal Code
60305-1876
Country
United States
Facility Name
Johnson County Clin-Trials
City
Lenexa
State/Province
Kansas
ZIP/Postal Code
66219-1389
Country
United States
Facility Name
Tekton Research
City
Wichita
State/Province
Kansas
ZIP/Postal Code
67218-2913
Country
United States
Facility Name
Versailles Family Medicine
City
Versailles
State/Province
Kentucky
ZIP/Postal Code
40383-1947
Country
United States
Facility Name
Velocity Clinical research
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70809
Country
United States
Facility Name
Benchmark Research
City
Metairie
State/Province
Louisiana
ZIP/Postal Code
70006
Country
United States
Facility Name
DelRicht Research
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70115
Country
United States
Facility Name
DelRicht Research
City
Prairieville
State/Province
Louisiana
ZIP/Postal Code
70769
Country
United States
Facility Name
Annapolis Internal Medicine
City
Annapolis
State/Province
Maryland
ZIP/Postal Code
21401
Country
United States
Facility Name
Velocity Clinical Research
City
Rockville
State/Province
Maryland
ZIP/Postal Code
20854
Country
United States
Facility Name
DM Clinical Research
City
Brookline
State/Province
Massachusetts
ZIP/Postal Code
02445-7113
Country
United States
Facility Name
Vida Clinical Studies
City
Dearborn Heights
State/Province
Michigan
ZIP/Postal Code
48127-2234
Country
United States
Facility Name
DelRicht Research
City
Gulfport
State/Province
Mississippi
ZIP/Postal Code
39503
Country
United States
Facility Name
Clay Platte Family Medicine
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64151-2411
Country
United States
Facility Name
Velocity Clinical Research
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68510
Country
United States
Facility Name
Velocity Clinical Research
City
Norfolk
State/Province
Nebraska
ZIP/Postal Code
68701
Country
United States
Facility Name
Excel Clinical Research
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89109-6209
Country
United States
Facility Name
CCT Research
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89119
Country
United States
Facility Name
Las Vegas Clinical Trials
City
North Las Vegas
State/Province
Nevada
ZIP/Postal Code
89030-7193
Country
United States
Facility Name
Rochester Clinical Research
City
Rochester
State/Province
New York
ZIP/Postal Code
14609-3169
Country
United States
Facility Name
Tryon Medical Partners
City
Charlotte
State/Province
North Carolina
ZIP/Postal Code
28210
Country
United States
Facility Name
Trial Management Associates
City
Wilmington
State/Province
North Carolina
ZIP/Postal Code
28403-6238
Country
United States
Facility Name
CTI Clinical Research Center
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45212
Country
United States
Facility Name
Velocity Clinical Research
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45219
Country
United States
Facility Name
Velocity Clinical Research
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45246
Country
United States
Facility Name
Centricity Research
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43213
Country
United States
Facility Name
WellNow Urgent Care & Research
City
Dayton
State/Province
Ohio
ZIP/Postal Code
45424-4019
Country
United States
Facility Name
Lynn Institute of East Oklahoma
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73111-3324
Country
United States
Facility Name
DelRicht Research
City
Tulsa
State/Province
Oklahoma
ZIP/Postal Code
74133
Country
United States
Facility Name
Tekton Research Inc
City
Yukon
State/Province
Oklahoma
ZIP/Postal Code
73099-9518
Country
United States
Facility Name
DM Clinical Research
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107-1530
Country
United States
Facility Name
Mercado Medical Practice
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19111-2432
Country
United States
Facility Name
DelRicht Research
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29407
Country
United States
Facility Name
Trial Management Associates
City
Myrtle Beach
State/Province
South Carolina
ZIP/Postal Code
29572-4612
Country
United States
Facility Name
Medical Care
City
Elizabethton
State/Province
Tennessee
ZIP/Postal Code
37643
Country
United States
Facility Name
DelRicht Research
City
Hendersonville
State/Province
Tennessee
ZIP/Postal Code
37075
Country
United States
Facility Name
Benchmark Research
City
Austin
State/Province
Texas
ZIP/Postal Code
78705-3298
Country
United States
Facility Name
Tekton Research
City
Austin
State/Province
Texas
ZIP/Postal Code
78745-1470
Country
United States
Facility Name
Tekton Research
City
Beaumont
State/Province
Texas
ZIP/Postal Code
77706-3061
Country
United States
Facility Name
Benchmark Research
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76135
Country
United States
Facility Name
Cyfair Clinical Research
City
Houston
State/Province
Texas
ZIP/Postal Code
77065
Country
United States
Facility Name
Texas Center for Drug Development
City
Houston
State/Province
Texas
ZIP/Postal Code
77081
Country
United States
Facility Name
DelRicht Research
City
McKinney
State/Province
Texas
ZIP/Postal Code
75070
Country
United States
Facility Name
Benchmark Research
City
San Angelo
State/Province
Texas
ZIP/Postal Code
76904-7610
Country
United States
Facility Name
Tekton Research
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
CCT Research
City
Pleasant View
State/Province
Utah
ZIP/Postal Code
84404
Country
United States
Facility Name
Ogden Clinic
City
Roy
State/Province
Utah
ZIP/Postal Code
84067
Country
United States
Facility Name
JBR Clinical Research
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84107
Country
United States
Facility Name
Meridian Clinical Research
City
Hampton
State/Province
Virginia
ZIP/Postal Code
23666
Country
United States
Facility Name
Velocity Clinical Research
City
Portsmouth
State/Province
Virginia
ZIP/Postal Code
23703
Country
United States
Facility Name
Wenatchee Valley Hospital & Clinics Campus
City
Wenatchee
State/Province
Washington
ZIP/Postal Code
98801
Country
United States

12. IPD Sharing Statement

Learn more about this trial

A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

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