HUMAN CHORIONIC GONADOTROPIN (HcG) VS MAGNESIUM SULPHATE (MgSo4) AS A TOCOLYTIC AGENT- A RANDOMIZED CONTROLLED TRIAL
Preterm Labor
About this trial
This is an interventional treatment trial for Preterm Labor
Eligibility Criteria
Inclusion Criteria: 4 uterine contractions per 20 min or 8 contractions per hour single live fetus Pregnancy less than 37 weeks Intact Membranes, Dilatation less than 3cm and effacement less than 80%. Exclusion Criteria: Cervical Dilatation more than 4 cm Abnormal vaginal bleeding Premature Rupture of membranes Cardiopulmonary compromised Fetal and Uterine anomalies
Sites / Locations
- Mother and Child Care Hospital, Shaheed Zulfiqar Ali Bhutto Medical University
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
HUMAN CHORIONIC GONADOTROPIN (HCG) Group
Magnesium Sulphate(MgSO4) Group
H.C.G. will be given in Group A and in a dose of 5000units intramuscular injection followed by a drip of 10,000 units in 500ml of dextrose 5%, at the rate of 20 drops per minute. Half hourly assessment of uterine contractions, maternal vital signs, fetal heart rate monitoring will be done.
4gm of MgSO4 will be given in Group B as intravenously as continuous dose followed by 2gm/hr till uterine quiescence is achieved.