Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
Postoperative Pain, Cesarean Section, Wound Heal
About this trial
This is an interventional supportive care trial for Postoperative Pain focused on measuring Cesarean section, Wound healing, Nerve block, Cortisol, Immune response
Eligibility Criteria
Inclusion Criteria: Patients scheduled for the elective cesarean section through Pfannenstiel incision under spinal anesthesia Age >18 American Society of Anesthesiologists (ASA) physical status II Body mass index < 40 mg/kg² >35 gestational weeks Exclusion Criteria: participant's refusal to participate in the study ASA physical status >II emergency cesarean section twin or triplets pregnancy history of allergy to the local anesthetic or any other drug used in this study (dexmedetomidine, acetaminophen, tramadol, nonsteroidal anti-inflammatory drugs) contraindications for spinal anesthesia or TAP block Drop out from the study: the change in anesthetic technique from spinal to the general anesthesia the need for the blood transfusion acute mastitis, puerperal endometritis, and/or wound infection developed in the first 72 hours postoperatively failed TAP block
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Experimental
Experimental
Group SA
Group L
Group D
No TAP block applied.
Ultrasound-guided bilateral TAP block (in-plane technique) will be performed in this group. Levobupivacaine 0.25 % 20 ml will be administered in the block on each side.
Ultrasound-guided bilateral TAP block (in-plane technique) will be performed in this group. Levobupivacaine 0.25 % 20 ml + dexmedetomidine 0,5 μg/kg will be administered in the block on each side.