Correlation of Timing of Pegfilgrastim Administration and the Improvement of PIBP and PRO.
Pegfilgrastim, Bone Pain, Chemotherapy
About this trial
This is an interventional treatment trial for Pegfilgrastim focused on measuring pegfilgrastim, bone pain, patient-reported outcomes, chemotherapy, Breast Cancer
Eligibility Criteria
Inclusion Criteria: Age greater than or equal to 18 years and less than or equal to 70 years. Pathologically or histologically confirmed diagnosis of malignant breast tumor. Able to receive the scheduled chemotherapy regimen as scheduled and the chemotherapy regimen is an intermediate to high risk febrile neutropenia regimen. Able to fill out questionnaires independently Exclusion Criteria: Suffering from severe bone pain due to other diseases currently (defined as bone pain >5 points on a 0-10 Numerical Rating Scale due to non-breast malignancies and their related treatments). Allergy or contraindication to chemotherapeutic agents or pegfilgrastim. Previous use of pegfilgrastim. Pregnancy or lactation. Refused to sign the informed consent.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Other
Other
Other
24h group
48h group
72h group
Pegfilgrastim is administrated 24 hours after completing the chemotherapy in the 24-hour group.
Pegfilgrastim is administrated 48hours after completing the chemotherapy in the 48-hour group.
Pegfilgrastim is administrated 72 hours after completing the chemotherapy in the 72-hour group.