Food Intake and IgA Microbiota in Anorexia Nervosa (AAMIAM)
Anorexia Nervosa, Healthy Volunteer
About this trial
This is an interventional basic science trial for Anorexia Nervosa focused on measuring anorexia nervosa, microbiota, gut-brain-axis, immunology (IgA)
Eligibility Criteria
Inclusion Criteria: female subject, adult, affiliated to a social security system, under the care of the eating disorder department of university hospital of st Etienne presenting a diagnosis of pure restrictive anorexia nervosa. For acute subgroup : BMI between 13 and 17.5 kg/m2, patient with a first episode of restrictive anorexia nervosa or with hyperphagic episodes. For the chronic subgroup: BMI between 13 and 17.5 kg/m2, disease evolving for more than 5 years. For Healthy volunteer: BMI between 20 and 24 kg/m², stable weight for the last 3 months, no eating disorder or history of eating disorder Exclusion Criteria: patient does not understand French. laxative treatment in progress or stopped for less than 15 days, antibiotic treatment in the two months preceding inclusion, pre-pro or symbiotic treatment in progress or in the month preceding inclusion, patient with one of the following comorbid disorders: celiac disease, chronic inflammatory bowel disease, lactose intolerance, unstabilized hyperthyroidism, unstabilized diabetes, subject under legal protective measures.
Sites / Locations
- Chu Saint-EtienneRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Placebo Comparator
Acute anorexia nervosa
Chronic anorexia nervosa
Healthy control
patient diagnose for a first episode of pure restrictive anorexia nervosa will be included. They will have stool sample and Food intake evaluation.
Patient diagnose for anorexia nervosa at least 5 years ago and still maintaining a significant thinness will be included. They will have stool sample and Food intake evaluation.
Healthy Patient will be included. They will have stool sample and Food intake evaluation.