Autophagy in Paediatric Crohn's Disease (P-IBDphagy)

Inclusion Criteria: For Crohn's Disease group : Age between 6 and 17 inclusive Patients with a weight > 25 kg at the time of inclusion Patients with Crohn's disease requiring ileocolonoscopy (diagnosis or follow-up) Mild to severe Crohn's disease consistent with PCDAI disease activity score Patients on nutritional therapy (Modulen/Modulife), corticosteroids, salicylic derivatives, immunosuppressants, biotherapies (anti-TNF, vedolizumab and ustekinumab) or without treatment Consent form signed by the patient or the holder(s) of parental authority. Affiliation to a social security scheme or beneficiaries of a similar scheme. For Control group: Between 6 and 17 years old included Presenting a weight > 25 kg at the time of inclusion Without a diagnosis of Crohn's disease Requiring evaluation by ileoendoscopy Consent form signed by the patient or the holder(s) of parental authority. Affiliation to a social security scheme or beneficiaries of a similar scheme. Exclusion Criteria: Refusal to participate in the protocol Intercurrent infection Ongoing antibiotic treatment Patient involved in another interventional study protocol including an exclusion period still in progress at pre-inclusion Pregnant, parturient or breastfeeding women (on questioning) Persons deprived of their liberty by a judicial or administrative decision Persons subject to psychiatric care Persons admitted to a health or social establishment for purposes other than research