Effects of Repetitive Transcranial Magnetic Stimulation on Cerebral Autoregulation in Patients With Acute Ischemic Stroke

Inclusion Criteria: Age ≥ 18 years, both sexes; Clinically definite diagnosis of acute ischemic stroke; Baseline National Institute of Health Stroke Scale (NIHSS) score ≤25; Pre-onset modified Rankin Scale (mRS) score ≤1; Randomized and initiated transcranial magnetic stimulation within 1 week of onset; Subject or legal representative agreed to the treatment and signed the informed consent. Exclusion Criteria: Presence of a medical condition such as severe cognitive impairment or mental impairment; Patients with serious physical diseases or who have had craniocerebral surgery; Previous history of epilepsy, family history of epilepsy or presence of seizure provoking factors; Pregnancy or breastfeeding; The presence of metal foreign bodies near the stimulation site, such as intracranial metal implants, cochlear implants, built-in pulse generators (brain pacemakers, cardiac pacemakers), etc.; Patients who are unable to complete cerebral autoregulation, or bilateral temporal window penetration poorly; life expectancy of ≤3 months or inability to complete the study for other reasons; unwillingness to be followed up or poor treatment compliance; Those who are participating in other clinical investigators, or who have participated in other clinical studies within 3 months prior to enrollment, or who have participated in this study; Other conditions that the investigators deemed unsuitable for enrollment.