Influence of Implant Component Materials on Peri-implant Soft Tissue Horst Response. (PISTI)
Dental Implants, Soft Tissue Inflammation, Immunohistochemistry

About this trial
This is an interventional prevention trial for Dental Implants focused on measuring Dental implants, Soft Tissue Inflammation, Abutment materials, Immunohistochemistry, histometry, Peri implant tissues, dental material, Dental abutments, histology, peri implant tissue changes
Eligibility Criteria
Inclusion Criteria: Needing implant therapy One or more missing teeth in the posterior area of either maxilla or mandible Good systemic health (ASA I/II) Full mouth plaque score (FMPI) lower than or equal to 25% The tooth at the implant site(s) had to be extracted or lost at least 12 weeks prior to implant placement 3 mm of keratinized mucosa in the bucco-lingual dimension with bone crest allowing at least a regular diameter implant (4.1 mm). Exclusion Criteria: Autoimmune disease requiring medical treatment Medical conditions requiring prolonged use of steroids, use of bisphosphonates and denosumab intravenously or in oral use Pregnancy or breastfeeding women Alcoholism o chronical drug abuse Immunocompromised patients Uncontrolled diabetes Smokers (more than 5 cigs/day) Implant diameter under 4 mm (narrow implant) Infection (systemic or local) The site was excluded if it was previously treated with socket preservation techniques, presented untreated local inflammation, mucosal diseases or oral lesions, history of local irradiation therapy or persistent intraoral infection.
Sites / Locations
- Hospital University of Liège (CHU-Ulg)
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Experimental
Experimental
Titanium abutment
Dental resin abutment
Polyetheretherketone abutment
Titanium (Ti) grade 5 titanium abutment
Dental resin (Re) Optibond ™ FL, Kerr Dental abutment
Polyetheretherketone (PEEK) Polyetheretherketone abutment