Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety
Posttraumatic Stress Disorder, Anxiety Disorders
About this trial
This is an interventional treatment trial for Posttraumatic Stress Disorder focused on measuring PTSD, Anxiety, Veterans, Service Members, Reservists, Treatment
Eligibility Criteria
Inclusion Criteria: Veteran/Service Member at least 18 years old Current diagnosis of at least one anxiety-based disorder: Posttraumatic Stress Disorder, Panic Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Other Specified Trauma- and Stressor-Related Disorder, Other Specified Anxiety Disorder, and Unspecified Anxiety Disorder (based on ADIS-5) Moderate-to-poor life enjoyment and satisfaction as indicated by a score of 47 or lower on the QLES-Q-SF Stable on psychotropic medication for 4 weeks before study participation Willing to be randomized to treatment condition Exclusion Criteria: Active symptoms of mania or psychosis at baseline (based on ADIS-5) Depression with active suicidal ideation and intent that would preclude treatment (based on ADIS-5 & BDI-II) Moderate-to-severe cognitive impairment as indicated by the SLUMS (a score below 20) Veterans/Service Members with comorbid substance/alcohol use or dependence are study eligible but must agree to reduce and limit their use of substances during the active course of treatment, particularly during exposure exercises. If they do not agree to this, they will be excluded Undergoing concurrent transdiagnostic CBT specifically targeting any of the above-mentioned disorders
Sites / Locations
- Michael E. DeBakey VA Medical CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Active Comparator
iTCBT-I (Intensive Transdiagnostic Cognitive Behavioral Therapy-Individual)
iTCBT-G (Intensive Transdiagnostic Cognitive Behavioral Therapy-Group)
Treatment as Usual (TAU)
Patients in this arm will receive transdiagnostic CBT delivered in an intensive individual format over 2 weeks. Intensive Transdiagnostic Cognitive Behavior Therapy-Individual (iTCBT-I): Participants randomized to this condition will receive 12 hours of treatment in four 3 hour sessions, over a 2-week period. Treatment consists of psychoeducation, cognitive restructuring, and exposure exercises. For treatment non-responders (i.e., BAI score decrease < 10), patients will receive 4 additional 90 minute sessions of individual therapy over a 2-week period (iTCBT-Enhanced). These sessions will identify areas where participants might benefit from more in-depth focus on specific concepts taught in the treatment.
Patients in this arm will receive transdiagnostic CBT delivered in an intensive group format over 2 weeks. Intensive Transdiagnostic Cognitive Behavior Therapy-Group (iTCBT-G): Participants randomized to this condition will receive 12 hours of treatment over a 2-day period (6 hrs each day). Treatment consists of psychoeducation, cognitive restructuring, and exposure exercises. For treatment non-responders (i.e., BAI score decrease < 10), patients will receive 4 additional 90 minute sessions of individual therapy over a 2-week period (iTCBT-Enhanced). These sessions will identify areas where participants might benefit from more in-depth focus on specific concepts taught in the treatment.
Patients in this arm will not receive transdiagnostic CBT but will receive treatment as usual, which may include other forms of psychotherapy and/or medication.