Video Game Hearing Tests for Remote Monitoring of Ototoxicity (VAROT)
Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss, Hearing Loss
About this trial
This is an interventional diagnostic trial for Aminoglycoside Toxicity
Eligibility Criteria
Inclusion Criteria: All patients ≥16 years old intended to receive >1 day of an ototoxic agent (Pathway 1) All patients ≥16 years old (Pathways 2 and 3) Able to provide informed consent to participate in study (written and witnessed). Exclusion Criteria: Inability of patient to provide informed consent. Patients with previous diagnosed visual impairment that cannot be corrected with glasses. Inability to attend audiology appointments due to state of health. Pregnant women.
Sites / Locations
- Guy's & St Thomas' NHS Foundation TrustRecruiting
- University Hospitals Dorset NHS Foundation TrustRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
No Intervention
Experimental
No Intervention
Monitoring of ototoxicity
Tablet-based audiometry validation
Audio-training - intervention arm
Audio-training - control arm
Video game hearing tests will be used to determine if they can effectively monitor changes in hearing function over time remotely.
Further validation of tablet-based audiometry compared to formal sound-booth audiometry.
Audio-training with video game hearing tests will be used to determine if it can improve spatial hearing perception.
No audio-training but video game hearing tests will be used as a comparator arm to identify if audio-training can improve spatial hearing perception.