Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery
Intensive Care Unit Delirium
About this trial
This is an interventional prevention trial for Intensive Care Unit Delirium focused on measuring open heart surgery, sedation, dexmedetomidine, postoperative delirium
Eligibility Criteria
Inclusion Criteria: patients undergoing open heart surgery with the use of cardiopulmonary bypass (including coronary artery bypass grafting, valve repair/replacement, and combined) left ventricular ejection fraction (LVEF) >40%. Exclusion Criteria: preoperative atrial fibrillation previous history of interventionally treated arrhythmias second and third degree atrioventricular block bradycardia with heart rate ≤50/min pacemaker renal or hepatic insufficiency emergency procedures history of serious mental illness, delirium, and severe dementia
Sites / Locations
- Institute of Cardiovascular Diseases of VojvodinaRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Dexmedetomidine
Propofol
Evaluate the effects of dexmedetomidine for sedation of patients in the intensive care unit after open heart surgery
Compare the clinical outcomes of the experimental group with the standard of care, i.e. sedation with propofol