Low-Intensity Focused Ultrasound for Cocaine Use Disorder
Cocaine Use Disorder, Cocaine Dependence, Cocaine Abuse
About this trial
This is an interventional health services research trial for Cocaine Use Disorder focused on measuring Substance Use Disorders, Chemically-Induced Disorders, Substance-related disorders, Cocaine Addiction, Cocaine
Eligibility Criteria
Inclusion Criteria: Ages 18 years and older with a history of cocaine use disorder Have a current (past 6 months) DSM-5 diagnosis of cocaine use disorder (4 or more symptoms) assessed using the MINI neuropsychiatric interview Have a blood alcohol content by breathalyzer, equal to 0.000 when informed consent document is signed Ability to abstain from cocaine use at key points during study Willingness and ability to comply with scheduled visits and study procedures Ability to lie down for extended periods of time for imaging tests Will have reliable transportation throughout study Will have a stable residence during the 2 weeks prior to randomization and not be at risk of losing housing in next 2 months Must meet criteria to have magnetic resonance imaging (MRI) Exclusion Criteria: • Please contact PI or Study Coordinator for more details.
Sites / Locations
- UVA Center for Leading Edge Addiction ResearchRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Low-Intensity Focused Ultrasound (LIFU)
Sham LIFU
All subjects to receive LIFU and Sham in a randomized order.
All subjects to receive LIFU and Sham in a randomized order.