The Effect of Erythropoietin on Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
About this trial
This is an interventional treatment trial for Acute Respiratory Distress Syndrome focused on measuring Erythropoietin, ARDS, Lung Water Clearance
Eligibility Criteria
Inclusion Criteria: Age≥18 years; Meeting diagnostic criteria for sepsis 3.0; Tracheal intubation and mechanical ventilation; Meeting the diagnostic criteria of ARDS Berlin; Willing to accept treatment and sign an informed consent form; Exclusion Criteria: Age <18 years; Pregnancy or lactation; Patients with malignant tumors; Recombinant human erythropoietin (rhEPO) allergic patients; Hemoglobin (Hb) ≥120g/L; have recently taken rhEPO (within 3 months) or participated in other clinical trials; History of thromboembolic disease (pulmonary embolism, heart attack, cerebral infarction, arteriovenous thrombosis); Inability or unwillingness to provide informed consent or to comply with the requirements of the study;
Sites / Locations
- SAHWenzhouMURecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Erythropoietin group
0.9%NS
intravenous injection of 40000iu of rhEPO
intravenous injection of the same volume of 0.9%NS as the test group