Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool
Allergic Contact Dermatitis
About this trial
This is an interventional prevention trial for Allergic Contact Dermatitis
Eligibility Criteria
Allergic participants: Inclusion criteria Positive (at least one reading) or doubtful patch test (at least two readings) result to hydroperoxides of Linalool within the last ten years Aged 18 years or older Received written and verbal information of the study Signed written consent form Exclusion criteria Active eczema in test areas (volar forearms) Pregnancy or breast feeding Treatment with topical corticosteroids or other immune suppressants on/near test areas within two weeks prior to study start Systemic immune-suppressant treatment within seven days prior to study start UV exposure of test areas within three weeks prior to study start Unable to cooperate or communicate with the investigators Healthy controls: Inclusion criteria Aged 18 years or older Received written and verbal information of the study Signed written consent form Exclusion criteria Known or possible contact allergy to hydroperoxides of Linalool Known contact allergy to other fragrance allergens Active eczema or other known relevant skin diseases Pregnancy or breast feeding Treatment with topical corticosteroids or other immune suppressants on/near test areas within four weeks prior to study start. Systemic immune-suppressant treatment within four weeks prior to study start. UV exposure of test areas within three weeks prior to study start. Participation in other clinical studies within four weeks prior to study start. Unable to cooperate or communicate with the investigators.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Allergic participants
Healthy participants