To Evaluate Clinical Efficacy and Safety of Diabetes-Specific Formula (Nutren Diabetes)

Inclusion Criteria: 1. Male or female aged 18-75 years old (inclusive); 2. Diagnosis of diabetes, and stable use of hypoglycemic drugs for about 1 month (refer to Guidelines for the Prevention and Treatment of Type 2 Diabetes Mellitus in China (2020) for the diagnosis of diabetes); 3. Glycosylated hemoglobin (HbA1c) <8.5%; 4. Inability to feed orally; 5. It is estimated that tube feeding would be required for more than 9 days; 6. Patients or their guardians (or authorized personnel) have fully understood the study procedures of this trial and are willing to sign the informed consent form (ICF). Exclusion Criteria: 1. Subjects with congenital metabolism disorder or allergy to any ingredient in the product (such as whey protein, milk protein concentrate, soybean lecithin); those with congenital intolerance to fructose; 2. Patients who are not suitable for enteral nutrition, such as those with active gastrointestinal (GI) hemorrhage, intestinal ischemia, paralytic/mechanical ileus, decreased GI tension, stress ulcer, as well as severe abdominal distension, diarrhea and other digestive and absorptive dysfunction; 3. Subjects with severe local broken skin which affects the use of continuous glucose monitoring (CGM) system; 4. Subjects who have concurrent severe malnutrition (body mass index [BMI] <15), severe hypertriglyceridemia (triglyceride≥5.6 mmol/L), severe hypoproteinemia (albumin<20 g/L), severe immunosuppression (neutrophils<1500/mm3 or lymphocytes<500/mm3), severe anemia (hemoglobin<60 g/L), severe infection, high fever and other stress conditions; 5. Subjects with fasting C-peptide < 100 pmol/L (0.3 ng/mL); 6. Subjects who are receiving intracranial pressure reduction therapy; 7. Patients with active malignant tumor (except for glioma, meningioma) or in the period of radiochemotherapy; 8. Patients with severe cardiac failure (New York Heart Association [NYHA] Class IV); those with severe liver or renal impaired function (glomerular filtration rate < 30 mL/min/1.73 m2, or levels of transaminases or transpeptidases more than 3 times the upper limit of normal); or those with conditions such as active hyperthyroidism, treatment-resistant hypothyroidism; 9. Subjects with one of the following conditions: hemodynamic instability, life-threatening multiple injuries, as well as severe acidosis, shock, sepsis; 10. Recent (within 3 months) acute complications of diabetes, such as diabetic ketoacidosis, hyperosmolar hyperglycemic syndrome; 11. It is expected to perform magnetic resonance imaging during the routine study; 12. Subjects who have used systemic glucocorticoid therapy within 2 weeks prior to screening or are expected to use during the study; 13. Women who are pregnant or plan to become pregnant or are breastfeeding; 14. Life expectancy ≤ 30 days; 15. Participated in other interventional clinical trials within 4 weeks prior to screening, including those involved in drugs, nutritional preparations, medical devices, etc.; 16. Other cases not eligible for this study in the investigator's opinion, such as inflammatory bowel disease (Crohn's disease or ulcerative colitis), acute pancreatitis, unstable vital signs, and if it does, the reasons for ineligibility should be recorded.