Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer Patients
Head and Neck Cancer Patients
About this trial
This is an interventional treatment trial for Head and Neck Cancer Patients focused on measuring xerostomia, thyme honey, nitric oxide
Eligibility Criteria
Inclusion Criteria: Patients referred to non-palliative head and neck radiotherapy Total dose of radiation received (50-70 Gy) Patients with complaint of xerostomia Age 25-65 years old Objective dry mouth score from ( 2-5) Subjective dry mouth score from (1-4) Undergoing radiotherapy for at least three weeks Can independently complete the questionnaire Exclusion Criteria: Have confirmed systemic diseases or medications associated with xerostomia Have a known allergy to honey Patients who had salivary glands removal surgery Patients with salivary gland diseases or malignancy Vulnerable groups such as pregnant females, prisoners, mentally and physically handicapped individuals.
Sites / Locations
- faculty of dentistry- Ain shams university
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
thyme honey
Saline
oral rinses (20 ml of thyme honey diluted in 100 ml of purified water) 3 times per day starting in the 4th week of radiotherapy and for one month after completion of radiotherapy. (Charalambous et al.,2017)
oral rinses with saline 3 times per day starting in the 4th week of radiotherapy and for one month after completion of radiotherapy.