The Effect of Bicarbonate Profiling in Dialysis Fluid on Phosphate Removal During Hemodialysis and Blood pH
Phosphorus Metabolism Disorders, Acid-Base Balance Disorder
About this trial
This is an interventional treatment trial for Phosphorus Metabolism Disorders focused on measuring phosphorus, hemodialysis, bicarbonate, acidosis, alkalosis
Eligibility Criteria
Inclusion Criteria: stable general condition hemodialysis more than 3 months Dialysis 3 times a week/ 4 hours +/- 20 minutes Dialysis with arterio-venous fistulas bicarbonate titer before hemodialysis 22-24 mmol/l Exclusion Criteria: diabetes mellitus cachexia inflamation processes usage of sevelamer last month utrafiltration during dialysis more than 2500 ml
Sites / Locations
- Wieliczko Monika
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Group 1: B) Dbic 35 -30 mmol/L C) Dbic 30- 35 mmol/L
Group 2: C) Dbic 30- 35 mmol/L B) Dbic 35 -30 mmol/L
Week 1 - a constant Dbic 35 mmol/L -Treatment A. Week 2 - Dbic 35 mmol/L for the first two hours followed by 30 mmol/L for the remainder of the treatment- Treatment B. Week 3 - a constant Dbic 35 mmol/L (wash-out period). Week 4 - Dbic 30 mmol/L for the first two hours followed by 35 mmol/L for the remainder of the treatment -Treatment C.
Week 1 - a constant Dbic 35 mmol/L -Treatment A. Week 2 - Dbic 30 mmol/L for the first two hours followed by 35 mmol/L for the remainder of the treatment- Treatment C. Week 3 - a constant Dbic 35 mmol/L (wash-out period). Week 4 - Dbic 35 mmol/L for the first two hours followed by 30 mmol/L for the remainder of the treatment -Treatment B.