Effect of Systemic Isotretinoin on Serum Irisin Level in Acne Vulgaris Patients
Acne Vulgaris
About this trial
This is an interventional treatment trial for Acne Vulgaris
Eligibility Criteria
Inclusion Criteria: Cases with moderate and severe acne. Clinical diagnosis of acne Disease Patient not receive any treatment for acne vulgaris at least six months duration. Exclusion Criteria: 1 Pregnant and lactating women. 2. History of chronic liver disease . 3. Cardiovascular disorders . 4. Renal disease . 5. Hyperlipidemia . 6. Depression or mental illness. 7. Insulin dependent diabetes 8 Thyroid disease. 9 Osteoporosis or low bone mineral density . 10 Intestinal disorders such as inflammatory bowel disease or ulcerative colitis
Sites / Locations
- Qena Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Pateints with Moderate Acne
Pateints with Severe Acne
control
20 patients affected by Acne and More than half of the face is involved. Many papules and pustules, many open or closed comedones. One nodule may be present.
20 patients affected by Acne and Entire face is involved, covered with many papules and pustules, open or closed comedones and rare nodules
20 Health participants