HFNC vs NIPPV Following Extubation
Congenital Heart Disease
About this trial
This is an interventional treatment trial for Congenital Heart Disease focused on measuring Cardiac surgery for CHD, Cardiac Intensive Care Unit
Eligibility Criteria
Inclusion Criteria: All patients admitted to the CICU following cardiac surgery for CHD who are </= 1 year of age and/or weight </= 10 kg Exclusion Criteria: Patients who remain intubated for >/= 4 weeks Patients who have a tracheostomy in place prior to their cardiac surgery Patient enrolled in a competing research study Patients requiring extracorporeal membrane oxygenation (ECMO) support preoperatively Patients with birth weight < 2 Kg. Gestational age < 35 weeks at birth. Patients with extracardiac anomalies more than minor severity.
Sites / Locations
- Children's Healthcare of Atlanta
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
The high-flow nasal cannula (HFNC)
Non-invasive positive pressure ventilation (NIPPV)
The high flow nasal cannula (HFNC) is a unique mode of respiratory support that delivers warmed, humidified oxygen with a wide range of fractions of inspired oxygen (FiO2) and flow rate (liters/min) without an invasive device such as an endotracheal tube (breathing tube).
Non-invasive positive pressure ventilation (NPPV or NIPPV) is a unique mode of respiratory support that delivers pressurized, oxygen-enriched gas to the airway via the nose and/or oropharynx without a more invasive device such as an endotracheal tube (breathing tube).