The Links Between Executive and Linguistic Processes and Their Lesional Determinants From a Verbal Fluency Task (FluLEx)
Cognitive Neurodegenerative, Stroke, Verbal Fluency Disorders
About this trial
This is an interventional other trial for Cognitive Neurodegenerative focused on measuring stroke, cognitive neurodegenerative, Verbal Fluency Disorders
Eligibility Criteria
Inclusion Criteria: For Cognitive cortical neurodegenerative diseases PATIENTS informed consentPatients between 40 and 85 years old, French native language, Social Security affiliation, Can read, write and count (up to 36) and knows the alphabet Assessed in Amiens University Memory Clinic for: Mild severity impairment (MMSE> 19) or major severity impairment related to: AD according to Albert criteria and McKhann criteria DCL according to McKeith criteria FTLD according to Rascovsky criteria CBD according to Armstrong's criteria PSP according to Höglinger criteria For Stroke PATIENTS informed consent Patients between 40 and 85 years old, French native language, Social Security affiliation, Can read, write and count (up to 36) and knows the alphabet Having suffered a stroke, hospitalized in neurology, visualized by imaging Exclusion Criteria: Mental retardation or guardianship Other current or past brain condition affecting cognition, including: Severe head trauma Epilepsy prior to stroke still requiring previous treatment Parkinson disease, multiple sclerosis Brain tumor or brain radiation therapy Current or past schizophrenia or psychosis Active or past psychiatric impairments requiring a stay> 2 days in a specialized environment Contra indication to MRI Comorbidity with life expectancy <1 year Comorbidity affecting cognition in particular: Alcohol (> 3 glasses / day) or history of alcohol withdrawal syndrome Opiate or cocaine addiction or opiate withdrawal syndrome Renal failure (dialysis or creatinine clearance <30) Hepatic failure (spontaneous INR> 1.5 or PT <60%) Respiratory failure requiring oxygen therapy Heart failure (orthopnea> 2 pillows) Persistent vigilance disorder (NIHSS1a score ≤1) Cancer with paraneoplastic syndrome Treatment with gold salts, D Penicillamine or other treatment with cognitive effect Patient under guardianship or curators or private under public law Pregnant and / or lactating woman
Sites / Locations
- CHU AmiensRecruiting
Arms of the Study
Arm 1
Experimental
Cognitive cortical neurodegenerative diseases and stroke PATIENTS