Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation (OCS-PLP)
Phantom Limb Pain After Amputation, Lower Limb Amputation, Upper Limb Amputation
About this trial
This is an interventional treatment trial for Phantom Limb Pain After Amputation focused on measuring Phantom limb pain, Amputation, Operant Conditioning, Brain-Computer Interface, Electroencephalography, Tactile sense, Instrumental learning, Event Related Potentials
Eligibility Criteria
Inclusion Criteria: An upper (or lower limb) amputation more than 6 months ago, that has produced a moderate to severe hand/arm (or foot/leg) phantom limb pain, Male or female age 18 years or older, Medical clearance to participate, Reasonable expectation that ongoing medications, if any, will be maintained without change for at least 4 months from the start of the study, Able to provide informed consent and to understand the study instructions, Able to participate in the specific study procedures. Exclusion Criteria: Presence of other medically unstable condition (e.g., uncontrolled diabetes with recent weight loss, diabetic coma, frequent insulin reactions), A cardiac condition (e.g., history of myocardial infarction or congestive heart failure), Cognitive and/or attention difficulties affecting participant's ability to follow study directions, Known skin disorders or damaged skin at the anticipated at the scalp for EEG recording (e.g., unhealed wounds, broken skin). Metal implants above the chest
Sites / Locations
- Albany VA Medical Center Samuel S. Stratton, Albany, NYRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Intervention Group
Control Group
Intervention group receives peripheral stimulation with realtime operant conditioning feedback training.
Control group receives peripheral stimulation but without operant conditioning feedback.