Effect of Nonsurgical Periodontal Therapy (NSPT) on Rheumatoid Arthritis Subjects With Periodontitis
Periodontitis, Rheumatoid Arthritis
About this trial
This is an interventional treatment trial for Periodontitis focused on measuring periodontitis, rheumatoid arthritis, nonsurgical periodontal therapy, professional mechanical plaque removal, oral hygiene education
Eligibility Criteria
Inclusion Criteria: All RA patients who fulfill the American College of Rheumatology (formerly the American Rheumatism Association) 2010 revised criteria for the classification of RA and who are unresponsive to conventional RA treatment. At least 4 sites with probing pocket depths (PPD) ≥5mm and 4 sites with clinical attachment level (CAL) ≥3mm distributed in at least 2 quadrants (Papapanou et al, 2018) and will be designated as having Stage II and Stage III periodontitis in addition to Bleeding on Probing (BoP) score of >30% representing generalised inflammation (Chapple et al, 2017) Patients should have a minimum of 14 teeth present. Exclusion Criteria: Patients who are on antibiotic use during the previous 3 months before study Patients who have received nonsurgical periodontal treatment within 6 months and surgical periodontal treatment within 12 months before the study. Patients who have any concurrent systemic or debilitating conditions such as uncontrolled diabetes. Non Malaysian subjects Patients who are pregnant Presence of acute dental pain or infections
Sites / Locations
- Universiti MalayaRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Nonsurgical periodontal therapy
Delayed treatment
Subjects in the IG will be given non-surgical periodontal treatment comprising of oral hygiene instructions, scaling and root surface debridement. Scaling will be carried out with ultrasonic scaler. For root surface debridement (for sites with PPD >4mm), local anaesthetic will be administered and ultrasonic scaler and Gracey curettes will be used. The scaling and root surface debridement will be done in 2 sittings over 2 different days within a week. Oral hygiene instructions and additional supportive scaling and root surface debridement will be repeated at 3 months and 6 months if judged necessary (presence of sites with BOP and/or PPD ≥5mm).
Oral hygiene instructions at baseline and will be repeated at 3 months and 6 months. All subjects will receive scaling and root surface debridement at the end of the 6 month trial.