Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement
Hemodynamics, Transcatheter Aortic Valve Replacement, General Anesthesia
About this trial
This is an interventional treatment trial for Hemodynamics focused on measuring ciprofol, transcatheter aortic valve replacement, general anesthesia
Eligibility Criteria
Inclusion Criteria: patients planned for transfemoral transcatheter aortic valve replacement expected duration of surgery ≥ 1 and ≤ 3h patients undergoing general anesthesia no gender limit,age≥60 years,≤85 years BMI ≥18 and ≤30kg/m2 ASA physical status 3~4 be able to understand the procedures and methods of the trial and voluntarily sign the informed consent form Exclusion Criteria: predicted presence of difficult airway or previous history of difficult airway allergic to eggs, soy products, propofol, and opioids and their antidotes patients with shock or hypotension that is difficult to correct with vasopressor patients with mental, nervous system diseases, long-term use of sedatives or antidepressants HB < 10.0 g/dL (100 g/L) patients with previous long-term use of sedative and analgesic drugs patients with severe heart,lung,liver and kidney disease not suitable for participation in this study as assessed by the investigator
Sites / Locations
- The Second Affiliated Hospital of Zhejiang University anesthesiology departmentRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
group ciprofol
group propofol
Patients receive ciprofol for general anesthesia
Patients receive propofol for general anesthesia