Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics
Xerostomia
About this trial
This is an interventional supportive care trial for Xerostomia focused on measuring Xerostomia, Aloevera, Thyme honey, type 2 diabetes
Eligibility Criteria
Inclusion Criteria: Both gender, with type 2 diabetes mellitus only and suffering from xerostomia. Patients willing to follow all the instructions and attend all the study-associated visits. Exclusion Criteria: Patients who had received radiation therapy to the head and neck region. Patients with other systemic diseases known to cause xerostomia (Sjogren's syndrome, rheumatoid arthritis, systemic lupus erythematosus, hepatitis C virus, tuberculosis, or sarcoidosis). Patients using any other medication for their dry mouth condition (pilocarpine, cevimeline) 7 days before entering into the study. Patients requiring hospitalization for any medical problem during the study. Known hypersensitivity to the active ingredient of the product that will be used as assessed by the medical history questionnaire. Vulnerable groups such as mentally or physically handicapped individuals, pregnant females, prisoners.
Sites / Locations
- Faculty of dentistry Ain shams university
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
Aloevera group
Thyme honey group
Saline group
15 patients suffering from diabetes induced xerostomia that will receive aloe vera as mouthwash (20 ml of aloe vera 50%) 3 times per day for 4 weeks.
15 patients suffering from diabetes induced xerostomia that will receive thyme honey mouthwash (20 ml of thyme honey diluted in 100 ml of distilled water) 3 times per day for 4 weeks.
15 patients suffering from diabetes induced xerostomia that will receive saline mouthwash as a control group (20 ml of saline) 3 times per day for 4 weeks.