The Construction and Application of Therapeutic System of Intelligent Decision-Oriented Hemodynamic Organized Therapy for Shock Patients

Inclusion Criteria: Septic shock patients with norepinephrine>0.25ug/kg/min Exclusion Criteria: Under 18 years of age Acute coronary syndrome requiring treatment have been treated with VA-ECMO VV-ECMO treatment has been administered for less than 12 hours Patient is on posterior pituitary hormone Patients with liver failure with a Model for End-Stage Liver Disease (MELD) score ≥ 30 Patients requiring more than 500 mg of hydrocortisone or equivalent glucocorticoid daily as a fixed dose absolute neutrophil counts below 1,000/mm3 Patients with active bleeding who are expected to require (within 48 hours of study entry) transfusion of more than 4 units of red blood cell concentrate patients with active bleeding that is expected to require (within 48 hours of study entry) transfusion of more than 4 units of red blood cell concentrate malignancy or other irreversible disease or condition with an estimated 6-month mortality rate of ≥50% Confirmed or suspected acute mesenteric ischemia. If the investigator believes that the patient's condition is highly suspicious but not confirmed by conventional criteria The investigator may exclude a patient if, in the opinion of the investigator, the patient's condition is highly suspicious but not confirmed by conventional criteria, or if the treating physician has initiated empiric therapy. Likely death expected within 12 hours Family or physician plans to implement a palliative care plan for the patient