Efficacy of L-menthol on Breathlessness in Chronic Obstructive Pulmonary Disease (Ment-COPD)

Inclusion Criteria: The subject has given written consent to participate in the study Diagnosis of COPD confirmed by spirometry and a FEV1 < 80% of predicted post bronchodilator at baseline age 18 years or older able to cycle able to understand and talk Swedish to participate in the study procedures, as judged by the Investigator. Exclusion Criteria: Resting peripheral oxygen saturation (SpO2) < 92% hospitalization or clinical instability during the last four weeks treatment with supplementary oxygen at rest or during exercise contraindication to exercise testing in accordance with clinical practice guidelines expected survival shorter than six months as judged by the Investigator medical conditions including congestive heart failure, acute coronary artery disease, neuromuscular diseases, severe psychiatric illness, and olfaction disorder.