Coordinated Reset Deep Brain Stimulation for Essential Tremor
Essential Tremor, Upper Extremity Essential Tremor
About this trial
This is an interventional treatment trial for Essential Tremor
Eligibility Criteria
Inclusion Criteria: Diagnosis of Essential Tremor (ET) Age of 21 or over Will be implanted with Boston Scientific Vercise Rechargeable Genus deep brain stimulation (DBS) system 7 Tesla (7T) MRI pre-operative scan under Noam Harel PhD's (Center for Magnetic Research (University of Minnesota IRB #1210M22183) protocol "Imaging of DBS targets at 7T MRI" Planned post-operative CT scan Exclusion Criteria: History of musculoskeletal disorders that affect movement of the limbs or gait Other significant neurological disorder History of dementia or cognitive impairment (Mini-Mental Score < 26) Significant psychiatric disease On medication that could cause tremor Prior brain surgery Pregnant women Evidence of non-ET central nervous system disease or injury for at least three (3) months prior to implantation Any suspicion of Parkinsonian tremor, including presence of Parkinsonian features such as bradykinesia, rigidity, or postural instability Other significant medical disorder that could impede study participation
Sites / Locations
- University of MinnesotaRecruiting
Arms of the Study
Arm 1
Experimental
upper extremity ET
participants with upper extremity ET who are scheduled to undergo DBS in the thalamus.