Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
Pulpitis - Irreversible, Apical Periodontitis
About this trial
This is an interventional treatment trial for Pulpitis - Irreversible
Eligibility Criteria
Inclusion Criteria: • Patients suffering from symptomatic irreversible pulpitis. Tooth should give positive response to cold test Heamostatis should be achieved after complete pulpotomy Diagnosis is irreversible pulpitis with/without apical periodontitis The tooth is restorable and free from advanced periodontal disease Tooth is free from cracks or splits Patients should be free from any systemic disease that may affect normal healing and predictable outcomes. Patients who will agree to the consent and will commit to follow-up period. Patients with mature root (closed apices) Teeth with no periapical lesion, resorption or widening. Soft tissues around the tooth are normal with no swelling or sinus tract Mandibular posterior teeth only will be involved. Exclusion Criteria: • Patients with immature root apices. Patients with any systemic disease that may affect normal healing. Patients with periapical lesions or infections. If heamostasis couldn't be achieved within 5-10 minutes Pregnant females. Patients who could/would not participate in a 6 months follow-up. Patients with fistula or swelling Patients with necrotic pulp. Patients with old age. Badly destructed teeth Teeth that are non-restorable Teeth that require post and core build up
Sites / Locations
- Faculty of oral and dental medicine - Cairo UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Control group
Intervention group
After control of bleeding in teeth allocated to the control group i-PRF is to be injected first. The i-PRF will be injected into the root canal to a level 3 mm below the cementoenamel junction (CEJ) then a layer of premixed bioceramic putty is to be added for coronal sealing.
After control of bleeding in teeth allocated to the intervention group, i-PRF is to be mixed with Nano bioactive glass (Nano-BAG) powder to a putty consistency and injected into the root canal to a level 3 mm below the cementoenamel junction (CEJ), then a layer of premixed bioceramic putty is to be added for coronal sealing.