Donors Predisposed by Corneal Collagen Cross-linking in Deep Lamellar Keratoplasty for the Patients With Keratoconus
Keratoconus
About this trial
This is an interventional treatment trial for Keratoconus focused on measuring Corneal collagen cross-linking, Deep lamellar keratoplasty, Keratoconus
Eligibility Criteria
Inclusion Criteria: 1.The best corrected visual quality of frame glasses is less than 0.3,2.The best corrected visual quality of rigid gas permeable contact lens (RGPCL) is less than 0.5/ RGPCL intolerance,3.The anterior corneal surface curvature >55D,4.The thinnest corneal thickness is less than 400 μm. One of the above four items is met Patients must be willing and able to return for scheduled follow-up examinations for 36 months after surgery Ages:over 18 Years Exclusion Criteria: History of intraocular surgery Severe dry eye Severe eyelid and conjunctival scar Loss of vision in contralateral eye Pregnant and lactating women
Sites / Locations
- Zhongshan Ophthalmic Center, Sun Yat-Sen University
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
CXL graft group
Conventional graft group
Corneal donors predisposed by CXL were used and the conventional DALK procedure was conducted in patients
Corneal donors stored in corneal storage media were used and the conventional DALK procedure was conducted in patients