the Effect of High Caloric Oral Nutritional Supplements on Growth and Development of Malnourished Children (EHCONSGDMC)
Malnutrition, Child, Malnourishment, Nutritional Deficiency
About this trial
This is an interventional treatment trial for Malnutrition, Child focused on measuring Oral Nutritional Supplements, Physique Growth, Neuropsychological Development
Eligibility Criteria
Inclusion Criteria: Aged 1-3 years BMI for Age Z-score<-2 Height-for-age z score<-2 Total daily energy intake<75% of recommended nutrient intake The child's guardian is willing to participate in this study and sign an informed consent form. Exclusion Criteria: Chronic or severe infectious disease (e.g., chronic hepatitis, HIV or tuberculosis infection) Certain congenital or genetic diseases affecting physical growth and development (congenital heart disease, Down's syndrome, infantile anorexia nervosa, etc.), malignancies and use of drugs (diuretics, appetite stimulants, steroids and growth hormones, etc.) Severe gastrointestinal disorders (e.g., celiac disease, short bowel syndrome, inflammatory bowel disease, etc.) Acute and chronic respiratory/digestive tract infections within 2 weeks prior to enrollment Allergy or contraindication to any of the ingredients in the high-energy total nutrition formula used in this study Have used high-energy enteral nutrition preparations for the last 3 months
Sites / Locations
- Anhui Provincial Children's Hospital
- Children's Hospital of The Capital Institute of Pediatrics
- Growth, Development and Mental health of Children and Adolescence Center
- Guangzhou Women and Children's Medical Center
- Guiyang Maternity and Child Health Care Hospital
- Hunan Children's Hospital
- Nanjing Maternity and Child Health Care Hospital
- Jiangxi Maternal and Child Health Hospital
- Baoji Maternity and Child Healthcare Hospital
- Xianyang Children's Hospital
- Chengdu Women's and Children's Central Hospital,School of Medicine,University of Electronic Science and Technology of China
- Kunming Children's Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
high caloric oral nutritional supplements group
nutritional education and dietary guidance group
Participants aged 1 to 3 years who are malnourished (underweight and wasting). They will receive nutritional education,dietary instruction and daily high caloric oral nutritional supplements for 12 months.
Participants aged 1 to 3 years who are malnourished (underweight and wasting). They will receive nutrition education and dietary instruction.