Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid Carries
Dental Trauma, Local Anesthesia, Oral Cavity Disease
About this trial
This is an interventional other trial for Dental Trauma focused on measuring Topical Anesthesia, Topical Formulation, Oral Mucosa, Lidocaine, Prilocaine, Nanostructured Lipid Carrier
Eligibility Criteria
Inclusion Criteria: Healthy participants No lesions in the study area Have already been submitted to local anesthesia without intercurrence Exclusion Criteria: Used any drugs that change the pain sensibility 1 week before Smokers Alcoholic
Sites / Locations
- Michelle Franz Montan Braga Leite
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Placebo Comparator
Experimental
Experimental
Topical anesthetic available on the market - Lidocaine (2.5%), Prilocaine (2.5%)
Xanthan hydrogel 2%
Xanthan hydrogel (2%), Lidocaine (2.5%), Prilocaine (2.5%) in NLC
Xanthan hydrogel (2%), Lidocaine (2.5%), Prilocaine (2.5%)
Applied at palatal mucosa (first premolar region), for 2 minutes. After that, this formulation will be removed. 100 mg.
Applied at palatal mucosa (first premolar region), for 2 minutes. After that, this formulation will be removed. 100 mg.
Applied at palatal mucosa (first premolar region), for 2 minutes. After that, this formulation will be removed. 100 mg. Local Anesthetic encapsulated in nanostructured lipid carriers (NLC)
Applied at palatal mucosa (first premolar region), for 2 minutes. After that, this formulation will be removed. 100 mg.