Nutrients-fortified Egg Consumption on Eczema Condition in Individuals With Eczema
Eczema, Atopic, Inflammation; Skin, Eczema
About this trial
This is an interventional supportive care trial for Eczema, Atopic focused on measuring Egg, Vitamin D, Vitamin E, Antioxidant, Eczema, Omega-3 long chain polyunsaturated fatty acids
Eligibility Criteria
Inclusion Criteria: English-literate and able to give informed consent in English Male and female subjects, aged between 21 and 59 inclusive Healthy individuals with no comorbidities or on regular medication BMI between 18.5-25 kg/m2 Mild to moderate severity of eczema, which will also be determined using our questionnaires during screening visit Exclusion Criteria: Significant change in body weight (3 kg or more) in the past 3 months Significant exercise pattern over the past 3 months defined as high-intensity exercise of more than 3 hours per week Known food allergy to eggs Taking dietary supplements which may impact the study results Had been diagnosed or with a history of gastrointestinal disorders e.g. irritable bowel syndrome, constipation, diverticulitis Current smokers Consumes more than 2 alcoholic drinks per day i.e. one drink is defined as either 150ml of wine, 340ml of beer/cider or 45ml of distilled spirit Taking lipid-lowering and blood pressure controlling medications less than 3 years Pregnant or lactating women, or planning to conceive in the next 6 months Unwilling to stop the medication of eczema during the study, either topical creams or oral medications Hierarchical link (professional and familial ties) with the research team members Participating in another clinical study Having blindness in one eye or more, previously diagnosed eye diseases, or have had eye surgery Low quality macular pigment optical density results, determined during screening visit
Sites / Locations
- National University of Singapore
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Nutrients-fortified egg
Regular egg
Each subject will be provided with 2 nutrients-fortified eggs from N&N Agriculture Pte Ltd to consume daily for 12 weeks. They will be instructed to consume the eggs for breakfast with the following preparation methods: hard-boiling, half-boiling and steaming. Subjects are to continue their usual diet.
Each subject will be provided with 2 regular eggs to consume daily for 12 weeks. They will be instructed to consume the eggs for breakfast with the following preparation methods: hard-boiling, half-boiling and steaming. Subjects are to continue their usual diet.