NC Testing in LC & POTS
Postural Orthostatic Tachycardia Syndrome, Post Acute Sequelae of SARS CoV 2 Infection
About this trial
This is an interventional treatment trial for Postural Orthostatic Tachycardia Syndrome focused on measuring POTS, Long COVID, Cognitive
Eligibility Criteria
Inclusion Criteria: Patients with diagnosis of Long COVID SARS-COV2 test positive Symptoms > 12 weeks post COVID Subjective complaint of 'brain fog" or cognitive dysfunction Patients with diagnosis of Postural Orthostatic Syndrome (POTS) from the Calgary Autonomic Investigation and Management Clinic Subjective complaint of 'brain fog" or cognitive impairment Healthy participants Without POTS or "brain fog" Age 18 to 60 years Female and Male Able to give an informed consent Exclusion Criteria: Patients with overt causes for POTS (e.g., dehydration, prolonged bed rest) An inability to safely withdraw from medicine(s) that could make test interpretation difficult and impossible. Other factors which are in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies or an unpredictable schedule. Unable to give an informed consent.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
1500mL Normal Saline
50mL Normal Saline
1500mL of normal saline infused intravenously.
50mL of normal saline infused intravenously.