Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Knee Degenerative Osteoarthritis
Osteoarthritis
About this trial
This is an interventional treatment trial for Osteoarthritis
Eligibility Criteria
Inclusion Criteria: Those who fall under Kellgren-Lawrence grade 2 to 3 according to the criteria in accordance with ACR guidelines and X-ray findings used within 12 months VAS score exceeding 50mm An adult male and female over 50 years of age Preservative therapy Glucosamine chondroitin sulfate/physiological therapy and rehabilitation exercises, and joint injections of hyaluronic acid for more than 12 weeks A person who agrees to allow existing drug treatment during the clinical trial, but not to be subject to additional drug administration or new conservative treatment for symptom control Exclusion Criteria: A locally infected patient A person whose life expectancy is less than six months A person with symptoms of lower extremities that are considered secondary to atherosclerosis or arterial vascular disease (ex: claudication ischemic rest pain) A person diagnosed with rheumatism or infectious arthritis Who had previous knee surgery INR 2.5 or less than 30,000 platelets Anaphylaxis-causing iodine allergy Patients with renal dysfunction or impaired renal function who have been diagnosed with less than 45 GFR (eGFR) within the last 60 days Those who have a taboo on MR videos Pregnant women Other cases where it is deemed inappropriate to participate in this clinical trial at the discretion of the researcher
Sites / Locations
Arms of the Study
Arm 1
Experimental
Transcatheter Arterial Micro-Embolization
If abnormal blood vessels related to pain are identified by angiography, selective embolization is performed using Nexsphere-F.