Cardiac Arrest Bundle of cARE Trial (CABARET)
Cardiopulmonary Resuscitation, Cardiac Arrest, Out of Hospital Cardiac Arrest
About this trial
This is an interventional treatment trial for Cardiopulmonary Resuscitation focused on measuring Cardiac Arrest, Mechanical CPR, Cardiopulmonary Resuscitation, Impedance threshold device, Active compression decompression CPR, Head up cardiopulmonary resuscitation (HUP-CPR)
Eligibility Criteria
Inclusion Criteria: Adult patients (>18 year of age) who have suffered a cardiac arrest Body habitus is compatible with the bundle devices. Witnessed event Time of collapse was known with reasonable certainty to have been to be within 20 minutes. Exclusion Criteria: Visibly pregnant women Prisoners Traumatic cardiac arrest Drowning Hanging DNACPR Have been in witnessed cardiac arrest for an estimated time of 21 minutes or more
Sites / Locations
- University Hospital Southampton NHS Foundation trust
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Control (usual care)
Intervention 'bundle of care'
Usual care for a cardiac arrest patient with no deviation aside from application of a cerebral saturation monitor (Near-Infrared Spectroscopy NIRS) (when available).
The clinical team will follow a specific sequence of actions using three devices (Elegard, Lucas AD, and ITD-16), in addition to standard CPR. Firstly, they will place the ITD onto the i-gel) or ETT, followed by the Elegard device and the LUCAS AD. The team will also place a cerebral saturation monitor on (Near-Infrared Spectroscopy (NIRS)) (if they have access to one). After 2 minutes of CPR via the LUCAS AD with the ResQPOD-16 (ITD), the Elegard device will be turned on and activated to gradually elevate the head approximately 22cm from the ground to the back of the occiput. If necessary, the clinical team may choose to intubate the trachea at this point. Resuscitation will continue for at least 30 minutes or until ROSC is achieved. If ROSC is achieved, standard post ROSC guidelines will be followed.