The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne

Inclusion Criteria: Subjects 12 years of age until 45 years of age The presence of mild to moderate acne based on investigator global assessment. Presence of at least 10 inflammatory lesions and at least 5 non-inflammatory lesions Exclusion Criteria: The presence of severe acne as noted by the investigator global assessment. Those who are unwilling to discontinue oral probiotic-based supplementation, or supplement ingredients found in the study's oral product 1 month prior to enrollment. Those who are unwilling to discontinue topical antibiotics and topical benzoyl peroxide for 2 weeks prior to enrollment Those who are unwilling to keep their facial regimen the same throughout the study Individuals who have been on an oral antibiotic for acne within the previous one month. Individuals who are pregnant or breastfeeding. Individuals who have changed any of their hormonal based contraception or therapies within 3 months prior to joining the study. Individuals on oral contraceptive pills or progesterone or estrogen containing therapies Use of isotretinoin within the three months prior to enrollment. Individuals on finasteride or dutasteride Current tobacco smoker or a tobacco smoking history