Laser Acupuncture on Diabetes-induced Peripheral Neuropathy
Diabetic Peripheral Neuropathy
About this trial
This is an interventional treatment trial for Diabetic Peripheral Neuropathy focused on measuring diabetic peripheral neuropathy, laser acupuncture
Eligibility Criteria
Inclusion Criteria: female or male patients (aged over 18 years) with diabetes mellitus type II. patients have symptoms (numbness, tingling, burning, stabbing, shooting pain, etc.) and signs (symmetric decreased distal sensation, or decreased or absent ankle reflexes) of diabetic neuropathy. presence of abnormal nerve conduction study, or presence of neuropathy is likely tested by Semmes-Weinstein 10-g monofilament, or decreased vibration sensation tested by 128Hz vibration tuning fork patients who have completed titration of pain medication or stopped accepting physical therapy against DPN; must provide written informed consent. Exclusion Criteria: severe DPN with muscular weakness of the proximal leg muscles; neuropathy due to other reasons (such as HIVD, malignancy, severe renal disease, hepatitis, thyroid disease, vitamine B12 deficiency, virus infection (such as: human immunodeficiency virus infection, etc), syphilis, alcohol, neurotoxic drug use, inflammatory disease (such as chronic inflammatory demyelinating polyneuropathy), heavy metal intoxication, hereditary disease, etc) severe peripheral artery disease in Fontaine stage IV(Focal tissue necrosis, ulceration or gangrene); traumatic lesions of the nerves or vessels in the lower extremities; opioid use before inclusion in the study; regular use of cannabis or cannabinoids; severe mental illness; severe impairment of cognitive function; pregnancy or lactation obesity (BMI>35 kg/m2)
Sites / Locations
- Tainan Municipal An Nan Hospital-China Medical UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
laser acupuncture group
sham laser acupuncture group
This study will use the Handylaser Trion laser manufactured by RJ Laser, Germany. It will be used for 40 seconds to deliver 6 J of energy as a pulsed wave (Noiger E) at each acupoint near palms or plantar, such as bilateral LI 4, PC6, KI 3, LR 3. For distal points in the four limbs, the laser will be used for 40 seconds at each acupoint to deliver 6J of energy as a pulsed wave (Noiger B), such as bilateral LI11, GB 34, ST 36, SP 6.
This study will use the sham Handylaser Trion laser manufactured by RJ Laser, without any laser beam delivering. The acupoints of the sham-laser acupuncture are the same as those of the laser acupuncture group.