Pain and Trismus Control in Third Molar Surgery: Ibuprofen, Ketamine, and Their Combination
Molar, Third
About this trial
This is an interventional treatment trial for Molar, Third focused on measuring pain, trismus, analgesia, ketamine, Ibuprofen
Eligibility Criteria
Inclusion Criteria: Patients with a fully embedded third molar tooth in the mandible Patients with regular attendance for routine follow up Patients with a healthy general systemic condition Exclusion Criteria: Patients with a fully erupted or partially embedded third molar tooth in the mandible Patients who have previously experienced allergies to NSAIDs, local anesthetics, and ketamine Pregnant or breastfeeding patients Patients who have recently used a different group of NSAIDs for a different condition
Sites / Locations
- Erciyes University Faculty of DentistryRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Placebo Comparator
Intrafen group
Ketamine group
Combined group (Intrafen+Ketamine)
Control
Each patient in this group will be administered intravenous Ibuprofen (400 mg/8 ml i.v. infusion) for pre-emptive analgesic effect 60 minutes before surgical third molar extraction. Before the procedure, each patient in this group will be given 2 ml of local anesthesia.
Each patient in this group will be administered intravenous 100 ml saline (Poliflex 0.9% isotonic 100 ml solution) for a placebo effect 60 minutes before surgical third molar extraction. Before the procedure, each patient in this group will be given 0.3 mg/kg of ketamine (Ketalar 500 mg) in addition to 2 ml of local anesthesia.
Each patient in this group will be administered intravenous Ibuprofen (400 mg/8 ml i.v. infusion) for pre-emptive analgesic effect 60 minutes before surgical third molar extraction. Before the surgery, each patient in this group will be given 0.3 mg/kg of ketamine (Ketalar 500 mg) in addition to 2 ml of local anesthesia.
Each patient in this group will be administered intravenous 100 ml saline (Poliflex 0.9% isotonic 100 ml solution) for a placebo effect 60 minutes before surgical third molar extraction. Before the procedure, each patient in this group will be given 2 ml of local anesthesia.