Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia
Postural Orthostatic Tachycardia Syndrome, Hypocapnia, Hyperventilation
About this trial
This is an interventional basic science trial for Postural Orthostatic Tachycardia Syndrome focused on measuring Postural Tachycardia Syndrome (POTS), Young Females, Tilt Table Testing, Initial Orthostatic Intolerance
Eligibility Criteria
Inclusion Criteria: The investigators will recruit female POTS cases (N=80) and healthy female control subjects (N=40) aged 15-39 years, matched for BMI. POTS is a disease in which 80-90% are females. Therefore, the investigators will only recruit female POTS patients and controls. Exclusion Criteria: Any subjects with systemic disease or who cannot stop taking prescribed medications for at least 2 weeks prior to study.
Sites / Locations
- NewYork Medical CollegeRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Female Postural Tachycardia Syndrome (POTS) patients without orthostatic hyperpneic hypocapnia
Female POTS patients with orthostatic hyperpneic hypocapnia
Healthy Female vounteers
Female POTS patients without orthostatic hyperpneic hypocapnia identified by tilt table testing and respiratory monitoring.
Female POTS patients without orthostatic hyperpneic hypocapnia identified by tilt table testing and respiratory monitoring.
Healthy Female vounteers