Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel
Peri-implant Mucositis, Mucositis Oral
About this trial
This is an interventional treatment trial for Peri-implant Mucositis focused on measuring Hyaluronic Acid, Peri-implant mucositis, Sodium hypochlorite
Eligibility Criteria
Inclusion Criteria: Age ≥ 18 years; Non-smokers and smokers ( ≤ 10 cigarettes/day); Presence of at least 1 implant in mucositis, clinically and radiographically detected; The implant in mucositis (tissue-level or bone-level) must support a fixed prosthetic device (single crown, 3-element bridge), cemented or screwed. Exclusion Criteria: Cancer patients; Uncontrolled diabetic patients; Prolonged antibiotic treatment or anti-inflammatory treatment in the previous 6 months; Pregnant or breastfeeding patients; Implants that support mobile prosthetic products; Implants in peri-implantitis, detected clinically and radiographically.
Sites / Locations
- Semmelweis UniversityRecruiting
- University of Naples Federico IIRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
NaOCl + HA Group
NSMD Group
A NaOCl-based gel will initially be applied in the peri-implant sulcus for 30 seconds, without the need for flushing. Furthermore, mechanical therapy (NSMD) will be performed by means of an ultrasonic scaler with a plastic tip. Finally, the HA-based gel will be applied in the peri-implant sulcus by means of a blunt-tipped needle.
Control group will be treated only through a non-surgical mechanical therapy with curettes or scaler tips.